Cortexolone 17 alpha-propionate ( Cortexolone 17α-propionate;CB-03-01;Clascoterone )

Catalog No. M13075 CAS No. 19608-29-8

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Product Name

Cortexolone 17 alpha-propionate
Note

Research use only, not for human use.
Brief Description

Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist.
Description

Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist, displays a strong local antiandrogenic activity in hamster's flank organ test, does not exhibit antiandrogenic activity after subcutaneous injection in vivo.Other Indication Phase 3 Clinical
Synonyms

Cortexolone 17α-propionate;CB-03-01;Clascoterone
Pathway

Endocrinology/Hormones
Target

Androgen Receptor (AR)
Recptor

AndrogenReceptor
Research Area

Other Indications
Indication

Other Disease

CAS Number

19608-29-8
Formula Weight

402.53
Molecular Formula

C24H34O5
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CCC(O[C@]1(C(CO)=O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
Chemical Name

Pregn-4-ene-3,20-dione, 21-hydroxy-17-(1-oxopropoxy)-

1. Celasco G, et al. Arzneimittelforschung. 2004;54(12):881-6.
2. Trifu V, et al. Br J Dermatol. 2011 Jul;165(1):177-83.

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